WiseGuys Pizza Buffalo 1965 Seneca Street Buffalo NY 14210

Hot pizza. Saucy wings. A combo that hits harder than a Sunday night kickoff 🔥🍕 Whether you’re hosting Bills parties, grad parties, or just dinner with the kids — Wiseguys Pizza & Wing Combos bring the flavor every time. Big boxes, bold Buffalo taste, zero stress.

The biggest slices you’ll find on Seneca Street. 🍕 First come, first served — so we recommend ordering ahead!

Gooey cheese, cup-n-char, sweetened sauce — just the way Buffalo pizza should be. 🍕🔥

Nothing hits like an ice-cold Coca-Cola with a hot Buffalo-style pizza 🧊🥤🍕 Whether you’re grabbing slices, feeding the family, or loading up for game day — crack open a frosty Coke and let Wiseguys handle the flavor. Because great pizza deserves an ice-cold partner.

Breakfast done the Wiseguys way 🔥🍳 Fluffy eggs, crispy bacon, savory ham — loaded with melted yellow American, mozzarella & cheddar, all sitting on a rich homemade gravy base. Creamy, cheesy, and straight comfort-food energy. One bite and you already know… this ain’t your average morning.

When the basics ain’t smacking… it’s time to level up 😎🍕 A whole lineup of Buffalo-style specialty pizzas — bold flavors, real attitude, available in ALL sizes. Go ahead… surprise yourself and try something different tonight.

Mouth-watering Buffalo-style pizza since 1992 🔥🍕 Made the way the old man taught us — crispy, cheesy, no shortcuts. Personals. Larges. X-Large. Sheet Pizzas. Gluten-Free. However you want it… we’re cooking.

Finely chopped steak, seasoned chicken, Italian sausage, turkey & more stacked high with fresh sautéed onions — peppers and mushrooms if you’re feeling dangerous 😈🔥 Finished the Buffalo way on a toasted hoagie roll with melty cheese and straight street-corner attitude. Big. Messy. Built like a true 716 classic. Available on an 8", 12", or a seeded 18" roll… because around here we don’t do small energy 🍞💪

🍗 Boneless Wings… SouthBuffalo style, no excuses 🔥 Right here on Seneca Street, we’re tossing ‘em crispy, saucy, and reckless — from Hot 🔥 to Honey Mustard 🍯 to Loganberry 🍒 and everything in between. Perfect for game day, dinner with the kids, or when you just don’t feel like fighting with bones 😏 #SouthBuffalo #SenecaStreet

Don’t overthink it — sometimes you just need crispy Buffalo-style chicken fingers done right 🔥🍗 Golden fried, juicy inside, and ready to be dunked in whatever sauce matches your mood. Lunch, dinner, game night… or when cooking sounds like a bad life choice.

Homemade salads like grandma made every summer 🥗 Chef, Antipasto, Chicken Finger, Grilled Chicken, Souvlaki, Steak & more — fresh, stacked, Buffalo bold.

Golden garlic breads, soft pretzel sticks, dessert breadsticks, classic breadsticks — hot, buttery, and straight-up irresistible 🔥🥖 Crispy edges, fluffy centers, and that Buffalo-style flavor that hits different. Perfect for dipping, sharing… or not. South Buffalo cravings start here.

Ricotta. Mozzarella. Folded, fired, and built like a straight-up Wiseguys weapon 🔥🥟 Our Calzone comes loaded with creamy ricotta and melty mozzarella — then you make it dangerous… add any toppings you want for that extra charge and extra attitude. Buffalo-style comfort with a criminal record.

Choose your weapons the Wiseguys way 🍝🔥 Pastas, Pizza Packs, Chicken Wings, Boneless, Chicken Fingers, Subs & Wraps — stack it up with ANY side, ice-cold drinks to quench the thirst, and don’t forget the desserts to finish the job. 🎉 Having a party? Grad parties, Super Bowl parties, youth sports events, business meetings — we got you covered with catering. Just give us 24-hour notice and we’ll handle the rest, South Buffalo style.

🍟 Hot. Crispy. Shake-worthy. 🍟 Our French Fries don’t just show up… they show OFF. Upgrade to Specialty Fries or get ‘em Shaken in your favorite wing sauce — sweet, spicy, buffalo, or straight savage 🔥 Perfect for Bills parties, late-night cravings, or stealing a few off your kid’s plate (we won’t tell 😏).

Crunch Wraps & Pizza Logs — Buffalo Style Trouble 🔥🌯 Our Classic Pizza Logs (4ct) come crispy and ready to be shaken in ANY homemade wing sauce — because basic ain’t our style. The Crunch Wrap lineup is straight dangerous: Steak & Cheese, Mac & Cheese, Sausage & Hot Pepper, and Buffalo Chicken… all melty, messy, and built for dipping. South Buffalo flavor with street-corner attitude — choose your sauce and get reckless.

🍰 Sweet cravings don’t stand a chance at MaryJane’s Desserts 😍 Fried Dough… Cheesecake… Cannolis… Chocolate… Red Velvet — and honestly, who knows what she’s gonna come up with next 🔥 If you’ve got a sweet tooth, consider this your warning… once you start, there’s no turning back.

ham, salami, and capicola

Margherita capicola

baked on request

Sahlen’s ham & premium turkey

Sahlen’s smoked ham

Margherita Salami

Sausage, bacon, mozzarella & parmesan baked on garlic bread with fried onions and your choice of peppers

3 Pieces of U.S.D.A Ribeye steak, NOT CHOPPED, Grilled to perfection.

with bacon

Includes chicken, lettuce, tomato, onion, black olives, feta, and Greek dressing.

mozzarella & pepperoni

sausage, capicola, ham & salami (hot sauce optional)